7 in series with 2 in parallel with an R2 to Vf=1.2V, allowing a lower Vc that the 12AU7. It is virtually silent and has a very wide range. I have not measured the DC current.
LT 1481 - output tubes
The front-end uses ZBX1512 tubes, with the non-inverting input directly from the output, and the input resistors at the output. The first stage uses ZBX1512C tubes.
I have not measured the DC current.
A compact 6T6 power amp
References
Bibliography
Category:Audio amplifiersThe emerging role of phosphodiesterase-5 inhibitors in the management of pulmonary arterial hypertension.
Pulmonary arterial hypertension (PAH) is a rare disease characterized by uncontrolled vasoconstriction of the pulmonary vasculature leading to progressive right ventricular failure and death. Treatment of PAH is aimed at improving disease severity by controlling the morbidity and mortality associated with right heart failure. Pulmonary vascular remodeling in PAH is mediated by multiple pulmonary artery smooth muscle cell (PASMC) phenotypes, with the most common being a proliferative, contractile phenotype. Therapeutic agents that modify smooth muscle cell proliferation and contractility may represent effective treatments for PAH. Because of its ability to relax PASMCs, inhibit platelet aggregation and thrombus formation, and improve pulmonary arterial perfusion, sildenafil, the first selective phosphodiesterase-5 (PDE-5) inhibitor to be studied in clinical trials for PAH, has become an important treatment option for PAH patients with mild-to-moderate disease. Tadalafil, a newer PDE-5 inhibitor, has also been shown to be effective in PAH. More recently, prostacyclin analogues, endothelin-1 receptor antagonists, and sGC stimulators have also been shown to improve clinical outcomes in PAH patients. By altering the molecular mechanism underlying disease pathogenesis, these newer agents are also effective in PAH patients with more severe disease, a paradigm for future therapy in this challenging disease.Can we get a 2nd to this? I am starting to feel like a lab rat. I've been so depressed this week since I saw my doctor at the end of the week and they informed me that I need to start treatment again. I went to a more traditional medical
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